Related Experiment Video
Updated: Jan 7, 2026
Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
Published on: January 28, 2014
Biomarkers
Joanne Rodda1,2, Lindsey A Kuchenbecker3,4, Wyllians Vendramini Borelli5,6
1Kent and Medway NHS and Social Care Partnership Trust, Maidstone, Kent, United Kingdom.
Background:
Clinicians' views on clinical readiness of Alzheimer's disease (AD) blood biomarkers (BBM) are not well understood.
Method:
The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment Biofluid-Based Biomarkers Professional Interest Area conducted a survey to elicit clinician opinions on AD BBM implementation, including contexts of use, assay selection, reporting and result interpretation.
Result:
Clinician respondents (n = 212) practiced in Europe (56%), North America (24%), Caribbean and Central or South America (11%) and other continents (9%). Most respondents were medical doctors (80%) practicing in secondary or tertiary care (88%) (Table 1). For 56% of respondents, CSF AD biomarkers or amyloid PET were accessible, but 48% agreed and 52% disagreed with implementation of AD BBM in any clinical context (Table 2). Respondents emphasized the need for data from diverse populations and educational resources to support test interpretation.
Conclusion:
Surveyed clinicians generally agreed with published appropriate use recommendations but were divided on AD BBM readiness for clinical use.
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