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Updated: Jan 7, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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Drug Development

Apostolos Manolopoulos1, Konstantinos Avgerinos2, Qinghua Chen1

  • 1National Institute on Aging, Baltimore, MD, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 25, 2025
PubMed
Summary

Ketone Ester (KE) supplementation increased brain ketone levels and reduced brain glutamate in individuals with metabolic syndrome. This suggests potential neuroprotection and cognitive benefits for Alzheimer

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