Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

746
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
746
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

511
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
511

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Facial feature removal in magnetic resonance imaging scans of adults with Down syndrome: A de-facing methodological study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Abnormal amyloid PET usually represents intermediate/high Alzheimer's disease neuropathologic change.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Default mode network failure across the Alzheimer's disease spectrum.

Brain : a journal of neurology·2026
Same author

Multi-Contrast MRI Inputs Enable Self-Consistent Tissue Segmentation & Robust Perivascular Space Identification.

bioRxiv : the preprint server for biology·2026
Same author

Regional gene expression and brain atrophy in dementia with Lewy bodies: an imaging transcriptomics study.

NPJ Parkinson's disease·2026
Same author

Divergent white matter metabolic signature patterns indicate impending cognitive decline in aging and dementia.

Nature communications·2026
Same journal

Breaking barriers: Enhancing access to dementia clinical trials in the United Kingdom-Insights from the Scientific Advisory Board of the Dame Barbara Windsor Dementia Goals Programme.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Estimated labor market outcomes of people progressing from preclinical to early-stage Alzheimer's disease in the United States.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Amyloid exacerbates tau and alpha-synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Reply to "Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
See all related articles

Related Experiment Video

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

Biomarkers.

Christopher G Schwarz1, Carl M Prakaashana1, Walter K Kremers1

  • 1Mayo Clinic, Rochester, MN, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 25, 2025
PubMed
Summary
This summary is machine-generated.

De-facing software used in brain imaging research shows performance differences across ethnoracial groups. These differences are small and unlikely to impact current Alzheimer's disease study analyses.

More Related Videos

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

699

Related Experiment Videos

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

699

Area of Science:

  • Neuroimaging
  • Medical Informatics
  • Health Disparities Research

Background:

  • Automated de-facing software is crucial for protecting participant privacy in brain imaging studies.
  • Existing de-facing tools are primarily validated on non-Hispanic White populations.
  • Performance disparities in de-facing software across ethnoracial groups are not well understood.

Purpose of the Study:

  • To evaluate the performance of de-facing software across diverse ethnoracial groups in brain MRI.
  • To compare the impact of de-facing on neuroimaging measurements (cortical thickness, gray matter volume) across non-Hispanic White, African American, and Mexican American individuals.

Main Methods:

  • Utilized T1-weighted MRI data from 305 participants in the Health and Aging Brain Study: Health Disparities (HABS-HD) cohort.
  • Matched participants across three ethnoracial groups (non-Hispanic White, African American, Mexican American) by age, sex, and cognitive status.
  • Applied mri_reface software for de-facing and FreeSurfer for neuroimaging analysis, comparing differences in measurements between de-faced and original images across groups.

Main Results:

  • Significant differences in cortical thickness de-facing effects were observed between non-Hispanic White and Mexican American groups, and between African American and Mexican American groups.
  • Gray matter volume differences due to de-facing were significant between African American and Mexican American groups.
  • Observed differences in both cortical thickness and gray matter volume were generally small, with minimal regional impact.

Conclusions:

  • The performance of de-facing software varies significantly across ethnoracial groups.
  • Future research will focus on optimizing de-facing algorithms to ensure equitable performance.
  • Current versions of de-facing software produce differences unlikely to affect practical outcomes in neuroimaging analyses.