Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A fovea-centered retinal signature linked to plasma biomarkers in prodromal Alzheimer's disease.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026

Same author

Visual cognition as a marker of longitudinal disease progression in Huntington's disease.

International journal of clinical and health psychology : IJCHP·2026

Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Same author

Basic Science and Pathogenesis.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Same author

Alzheimer's Imaging Consortium.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Same author

Alzheimer's Imaging Consortium.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Same journal

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Same journal

Estimated labor market outcomes of people progressing from preclinical to early-stage Alzheimer's disease in the United States.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Same journal

Amyloid exacerbates tau and alpha-synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Same journal

Reply to "Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Same journal

Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

Biomarkers.

Unai Sainz-Lugarezaresti^1,2, Asier Erramuzpe^1,3, Iñigo Gabilondo^1,3

¹Biobizkaia HRI, Barakaldo, Bizkaia, Spain.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association

|December 25, 2025

Summary

This summary is machine-generated.

BegiBrainTool offers a computerized vision assessment for early detection of neurodegenerative diseases like Alzheimer's. This modular toolbox aids neurologists in patient monitoring and research.

More Related Videos

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

Related Experiment Videos

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

Area of Science:

Neuroscience
Ophthalmology
Gerontology

Background:

Aging European population drives increased neurodegenerative diseases, including Alzheimer's.
Neurologists require specialized tools for early detection of these disorders.
A comprehensive toolbox for visual capacity evaluation in neurodegeneration is currently lacking.

Purpose of the Study:

To introduce BegiBrainTool, a computerized modular battery of visual tests.
To assess spatial and dynamic vision, and autonomic visual responses for early detection of neurodegenerative diseases.
To provide a valuable tool for both clinical and research applications.

Main Methods:

BegiBrainTool comprises three PsychoPy-implemented modules: spatial vision, dynamic vision with eye-tracking, and autonomic response.
Spatial vision module assesses elementary and semantic processing via stimuli varying in frequency, contrast, and color.
Dynamic vision module uses moving stimuli, visual search, and flicker fusion tests with integrated eye-tracking and pupilometry.
Autonomic response module measures unconscious reactions using pupillary response, heart rate variability, and galvanic skin response.

Main Results:

The project is currently ongoing with preliminary validation of components and data collection protocols.
Anticipated outcomes include a validated, open-source tool suitable for clinical deployment.

Conclusions:

BegiBrainTool presents a novel, interdisciplinary approach to visual assessment for neurodegenerative disorders.
The modular, computerized tools and biometrics offer a platform for patient monitoring and longitudinal analysis.
BegiBrainTool can support neurologists in managing neurodegenerative cases and advance research on visual and autonomic markers of Alzheimer's disease.