Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Supportive care for talquetamab-related dysgeusia in multiple myeloma: mixed-methods evidence, nutrition-focused flowchart, and digital companion concept.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026
Same author

The functional neuroanatomy of event-based and time-based prospective memory, and its improvement.

Communications biology·2026
Same author

Talquetamab-Related Dysgeusia in Multiple Myeloma Compared to BCMA-Targeted Bispecifics and High-Dose Melphalan.

Cancer medicine·2025
Same author

Incentives and practice improve prospective memory performance in older adults.

Aging clinical and experimental research·2025
Same author

Multi-Targeting CAR-T Cell Strategies to Overcome Immune Evasion in Lymphoid and Myeloid Malignancies.

Oncology research and treatment·2025
Same author

Factors Explaining Age-Related Prospective Memory Performance Differences: A Meta-analysis.

The journals of gerontology. Series B, Psychological sciences and social sciences·2025

Related Experiment Video

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

Biomarkers.

Katharina Klink1, Jessica Peter1

  • 1University of Bern, Bern, Switzerland.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 25, 2025
PubMed
Summary
This summary is machine-generated.

Real-time fMRI neurofeedback successfully reduced hippocampal hyperactivity and improved pattern separation performance in individuals at risk for Alzheimer's disease. This technique shows promise for treating early-stage cognitive decline.

More Related Videos

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

Related Experiment Videos

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Medical Imaging

Background:

  • Mild Cognitive Impairment (MCI) is linked to hippocampal hyperactivity during pattern separation tasks.
  • This hyperactivity correlates with increased Alzheimer's disease (AD) pathology and cognitive decline.

Purpose of the Study:

  • To investigate if real-time fMRI neurofeedback can reduce hippocampal hyperactivity.
  • To determine if this reduction improves pattern separation performance in individuals at risk for AD.

Main Methods:

  • Seventy-eight participants (MCI or healthy) underwent real-time fMRI neurofeedback to downregulate hippocampal activity or a control region.
  • Cognitive assessments and fMRI scans were repeated one week after the neurofeedback sessions.

Main Results:

  • Targeted downregulation of hippocampal activity significantly reduced hyperactivity and improved pattern separation performance.
  • Control region neurofeedback had minimal impact on hippocampal activity and cognitive performance.
  • Results were consistent across subgroups defined by clinical diagnosis, amyloid risk, and biomarker status.

Conclusions:

  • Real-time fMRI neurofeedback is effective in downregulating hippocampal activity.
  • This intervention improves pattern separation performance in individuals at risk for AD.
  • The approach shows potential as a therapeutic strategy for early AD-related hippocampal dysfunction.