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Updated: Jan 7, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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Drug Development

JiMin Kim1,2, Dohui Ku1,2, InWook Park1,2

  • 1Yonsei Institute of Pharmaceutical Sciences, Incheon, Incheon, Korea, Republic of (South).

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 25, 2025
PubMed
Summary

A novel small molecule, IK-9j, effectively clears amyloid-beta (Aβ) aggregates, a hallmark of Alzheimer's disease (AD). This Alzheimer's drug candidate significantly improved memory in mouse models, offering therapeutic potential.

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