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Updated: Jan 7, 2026

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
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Exploring the genetic link between obstructive sleep apnea and obesity: A bidirectional Mendelian randomization study

Fuguo Cai1, Wei Hong2, Chaoliang Xiong3

  • 1Department of Otolaryngology Head and Neck Surgery & Shaanxi Provincial Key Laboratory for Precision Diagnosis and Treatment of Otorhinolaryngology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West Fifth Road, Xi'an, Shaanxi, 710000, China; Department of Otorhinolaryngology-Head and Neck Surgery, Shangrao People's Hospital (Affiliated Shangrao Hospital to Nanchang University), Shangrao, Jiangxi 334000, China.

Respiratory Medicine
|December 25, 2025
PubMed
Summary

Obstructive sleep apnea (OSA) and obesity share a two-way causal link, supported by genetic evidence. Addressing both conditions together is key to managing their combined health impact.

Keywords:
CausalityMendelian randomizationObesityObstructive sleep apnea

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