Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Group Design02:01

Group Design

10.1K
The most basic experimental design involves two groups: the experimental group and the control group. The two groups are designed to be the same except for one difference— experimental manipulation. The experimental group gets the experimental manipulation—that is, the treatment or variable being tested—and the control group does not. Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between...
10.1K
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

842
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
842
Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs01:15

Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs

154
Body:Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...
154

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Air purifiers in classrooms for infection control: a pilot study including a randomized multiple crossover trial to evaluate effectiveness in reducing particulate matter.

Trials·2026
Same author

Policy monitoring indexes targeting non-communicable diseases: protocol for a scoping review.

BMJ open·2026
Same author

Do studies of interventions to improve laypeople's critical thinking about health choices assess potential harms? A systematic review.

BMJ open·2026
Same author

Norwegian food system actors' perspectives on participating in a cross-sector research partnership: a qualitative study.

BMC nutrition·2025
Same author

Development of a framework of potential adverse effects of interventions to improve critical thinking about health choices: A mixed methods study.

F1000Research·2025
Same author

Informed decisions about public health and social measures.

Health research policy and systems·2025

Related Experiment Video

Updated: Jan 7, 2026

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
09:33

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India

Published on: December 23, 2022

2.6K

Classroom air purifiers for reducing school absence: study protocol for a pragmatic, cluster-randomised, parallel,

Runar B Solberg1, Sverre B Holøs2, Ingeborg Hess Elgersma3

  • 1Centre for Epidemic Interventions Research, Norwegian Institute of Public Health, Oslo, Norway runar.solberg@fhi.no.

BMJ Open
|December 25, 2025
PubMed
Summary

This study investigates if High Efficiency Particulate Air (HEPA) filter air purifiers reduce student absenteeism in primary schools. Findings will inform non-disruptive strategies for managing respiratory infections in classrooms.

Keywords:
COVID-19INFECTIOUS DISEASESRandomized Controlled Trial

More Related Videos

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

2.9K
A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

10.4K

Related Experiment Videos

Last Updated: Jan 7, 2026

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
09:33

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India

Published on: December 23, 2022

2.6K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

2.9K
A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

10.4K

Area of Science:

  • Public Health
  • Epidemiology
  • Environmental Health

Background:

  • Respiratory infections pose significant global health risks, with schools identified as high-transmission settings.
  • COVID-19 school closures disrupted education and well-being, highlighting the need for non-disruptive mitigation strategies.
  • Evidence for the effectiveness of High Efficiency Particulate Air (HEPA) filter air purifiers in reducing viral transmission in schools is limited.

Purpose of the Study:

  • To estimate the effect of portable HEPA air purifiers on student absenteeism in primary school classrooms.
  • To assess the impact of HEPA air purifiers on teacher absenteeism and respiratory infection rates.
  • To evaluate the cost-effectiveness and implementation of air purifiers in educational settings.

Main Methods:

  • A cluster-randomised, parallel, two-arm, group sequential superiority trial involving primary schools in Norway.
  • Randomisation of schools to receive either HEPA air purifiers or sham air purifiers.
  • Primary outcome: student absenteeism measured as aggregated full child days of absence at the class level, with an interim analysis for early stopping.

Main Results:

  • The study is designed to determine if HEPA air purifiers significantly reduce student absenteeism compared to sham purifiers.
  • Secondary outcomes include reductions in teacher absenteeism and self-reported respiratory infections.
  • A cost-consequence analysis will be performed if a statistically significant effect on the primary outcome is observed.

Conclusions:

  • This trial will provide crucial evidence on the efficacy of HEPA air purifiers as a non-disruptive intervention to mitigate respiratory infections in schools.
  • Findings will inform public health policies and school management strategies for improving indoor air quality and reducing school-related illness.
  • The study aims to offer practical solutions for maintaining educational continuity during respiratory virus seasons.