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Area of Science:

  • Gerontology
  • Neuroscience
  • Digital Therapeutics

Background:

  • Cognitive intervention therapy effectively improves cognitive function in mild cognitive impairment (MCI).
  • Existing digital cognitive rehabilitation programs face challenges with cultural and linguistic adaptation for Korean elderly.
  • Korean-developed programs often prioritize engagement over memory enhancement.

Purpose of the Study:

  • To assess the superiority of 'SuperBrain DEX' in improving cognitive function in MCI patients compared to a control group.
  • To evaluate the safety and efficacy of 'SuperBrain DEX' as a digital therapeutic intervention for MCI.
  • To address the need for culturally relevant cognitive interventions for the Korean elderly population.

Main Methods:

  • A 16-week randomized controlled trial involving 140 MCI patients aged 50-85.
  • Personalized cognitive training using 'SuperBrain DEX' with AI-driven adaptation.
  • Control group received a dementia prevention lifestyle booklet; efficacy assessed via K-RBANS, CDR, K-MMSE-2, and other cognitive tests.

Main Results:

  • Participant enrollment is complete with 140 individuals (100%) registered across 12 research institutions.
  • The study commenced in January 2024, with all participants enrolled.

Conclusions:

  • Results are pending and will be presented at an upcoming conference.
  • The study is poised to provide crucial data on the effectiveness of a novel, culturally adapted digital therapeutic for MCI.