Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Instrumental Activities of Daily Living in Older Adults with Epilepsy: A Cross-Sectional and Longitudinal Multicenter Study.

medRxiv : the preprint server for health sciences·2026
Same author

A multiverse analysis of the logical memory test and plasma biomarkers of Alzheimer's disease.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same author

Alzheimer's disease neuroimaging signature aids identification of cognitive impairment in older adults with early-onset epilepsy.

medRxiv : the preprint server for health sciences·2026
Same author

The IMPACT epilepsy Consortium: Exploring social drivers of health in epilepsy care to advance solution based initiatives.

Epilepsy & behavior : E&B·2026
Same author

Utility of the ADAS-Cog as a Cognitive Screening Tool in Older Adults with Epilepsy: A Multicenter Cohort Study.

medRxiv : the preprint server for health sciences·2026
Same author

Comparing normative and ipsative methods of IC-CoDE phenotype classification in frontal lobe epilepsy.

Epilepsy & behavior : E&B·2026
Same journal

Evidence for progressive neurodegeneration in iatrogenic cerebral amyloid angiopathy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Kat5 cKO mouse replicates biological domain signatures associated with Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Evaluation of CSF and plasma tau species as fluid surrogate candidates for tau PET in prodromal to moderate Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Associations of self-reported obstructive sleep apnea with cognition and dementia risk in cognitively unimpaired middle-aged adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Inflammation profiles in Alzheimer's disease relate to cognition and neurodegeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
See all related articles

Related Experiment Video

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

Biomarkers.

Deling He1, Rebecca E Langhough2,3,4,5, Erin M Jonaitis2,6,7

  • 1Department of Communication Sciences and Disorders, University of Wisconsin- Madison, Madison, WI, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 25, 2025
PubMed
Summary
This summary is machine-generated.

Replacing logical memory with proper name recall in cognitive tests enhances early detection of Alzheimer's disease (AD) changes. This modification improves tracking of cognitive decline linked to the AD blood biomarker p-Tau217.

More Related Videos

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

Related Experiment Videos

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

Area of Science:

  • Neuroscience
  • Biomarkers
  • Cognitive Science

Background:

  • The Preclinical Alzheimer's Cognitive Composite (PACC) aids in detecting early Alzheimer's disease (AD) cognitive changes.
  • Plasma p-Tau217 is a sensitive blood biomarker for AD, reflecting brain amyloid and tau accumulation.

Purpose of the Study:

  • To enhance the sensitivity of the PACC to AD neuropathological changes.
  • To evaluate the utility of replacing the Logical Memory subscore with a proper name recall subscore in the PACC.

Main Methods:

  • 824 participants from the Wisconsin Registry for Alzheimer's Prevention (WRAP) were analyzed.
  • Participants were grouped based on plasma p-Tau217 levels (negative, intermediate, positive).
  • Six PACC variants were constructed, including versions with proper name recall and animal fluency, and analyzed using linear mixed models.

Main Results:

  • Individuals with positive plasma p-Tau217 exhibited the fastest cognitive decline across composites.
  • Declines in PACC variants incorporating proper name recall were significantly faster than traditional PACC measures.

Conclusions:

  • Substituting proper name delayed recall for logical memory total score increases sensitivity in tracking cognitive decline related to the AD blood biomarker p-Tau217.
  • This novel language measure yields composites more sensitive to preclinical AD changes, with implications for screening and clinical trials.