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Clinical Manifestations.

Sheila Castro-Suarez1,2, Jonathan Adrian Zegarra-Valdivia1,3, Erik Alberto Guevara-Silva2

  • 1Global Brain Health Institute (GBHI), University of California San Francisco, San Francisco, CA, USA.

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Summary
This summary is machine-generated.

The Telephone Montreal Cognitive Assessment (T-MoCA) effectively screens for cognitive impairment in Parkinson's disease (PD) patients remotely. Educational background significantly influences cognitive performance in individuals with PD.

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Area of Science:

  • Neurology
  • Neuroscience
  • Gerontology

Background:

  • Mild cognitive impairment (MCI) and dementia are significant non-motor symptoms in Parkinson's disease (PD).
  • Remote cognitive screening is crucial for timely clinical decision-making in PD patients.
  • The Telephone Montreal Cognitive Assessment (T-MoCA) offers a practical solution for remote cognitive assessment.

Purpose of the Study:

  • To evaluate the efficacy of the T-MoCA in differentiating cognitive impairment levels in Parkinson's disease patients.
  • To explore the correlation between sociodemographic factors and cognitive performance in PD.

Main Methods:

  • A cross-sectional study conducted remotely in Lima, Peru (2022-2024).
  • 155 Parkinson's disease patients were screened using T-MoCA, Geriatric Depression Scale (GDS), and Pfeffer Functional Activities Questionnaire.
  • Statistical analyses included ANOVA for group comparisons and Spearman correlation for variable relationships.

Main Results:

  • The T-MoCA successfully differentiated between cognitively unimpaired (mean score 19.4), MCI (mean score 16.1), and dementia (mean score 10.1) groups.
  • Years of education showed a positive correlation with T-MoCA scores (abstraction, sentence repetition).
  • Higher T-MoCA scores correlated with lower functional dependence (Pfeffer Score).

Conclusions:

  • The T-MoCA is a validated remote tool for assessing cognitive status in Parkinson's disease.
  • Sociodemographic factors, particularly education, play a vital role in cognitive performance among PD patients.
  • Remote assessment tools like T-MoCA are essential for managing non-motor symptoms in PD.