Breaking the Barriers: Transseptal Puncture in Patients with Atrial Septal Defect Closure Devices
Gerardo Lo Russo1,2, Roberto Nerla1, Angela Sanseviero1
1GVM Care & Research, Maria Cecilia Hospital Cotignola, Italy.
Interventional Cardiology (London, England)
|December 26, 2025
Summary
Transseptal puncture (TSP) in patients with atrial septal occluders (ASOs) is challenging but manageable. Advanced imaging and techniques optimize success for left atrial interventions, minimizing risks.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Atrial septal defects and patent foramen ovale are prevalent congenital heart defects in adults.
- Atrial septal occluders (ASOs) are commonly used for percutaneous closure of these defects.
Purpose of the Study:
- To review techniques, applications, and strategies for transseptal puncture (TSP) in patients with ASOs during left atrial interventions.
- To highlight the challenges and solutions associated with TSP in this patient population.
Main Methods:
- Review of existing literature on TSP techniques and ASO management.
- Discussion of pre-procedural planning using transoesophageal echocardiography and cardiac CT.
- Description of advanced techniques like balloon-assisted tracking and radiofrequency energy delivery.
Main Results:
- TSP in patients with ASOs presents unique procedural challenges.
- Optimal puncture sites can be identified through native septum or across the ASO using advanced imaging.
- Specialized expertise and multimodality imaging are crucial for successful outcomes.
Conclusions:
- TSP is a critical procedure for various left atrial interventions, including pulmonary vein isolation and left atrial appendage occlusion.
- Careful planning and advanced techniques can overcome challenges associated with ASOs.
- Minimizing complications such as residual shunting and device deformation requires specialized skills.
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