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Postoperative Radiotherapy in Spinal Rosai-Dorfman Disease: A Case Report and Literature Review
Wajana Thaweerat1, Pittaya Dankulchai1, Sorranart Muangsomboon2
1Division of Radiation Oncology, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Introduction:
Rosai-Dorfman disease (RDD) is a rare non-Langerhans cell histiocytosis with no well-established treatment approaches. Surgery is typically indicated for symptomatic patients, but adjuvant treatment to reduce recurrence is infrequently addressed in the literature.
Case Presentation:
Herein, we describe the case of a 77-year-old woman with a neurological deficit and an infiltrative epidural soft tissue mass at the T3 to T9 levels, as revealed by magnetic resonance imaging (MRI). Following complete tumor resection, pathological examination confirmed spinal RDD. The patient subsequently received postoperative radiotherapy with a dose of 30 Gy in 15 fractions 4 weeks later. At the 18-month postoperative follow-up, the patient was clinically improved and her MRI at 1 year showed no recurrence.
Conclusions:
Postoperative radiotherapy in spinal RDD remains controversial due to insufficient clinical evidence. Nevertheless, few case reports did not show treatment-related complications.
