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Federica Cacciamani1,2, Graziella Mangin Laignel2, Audrey Gabelle3,4

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Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 26, 2025
PubMed
Summary
This summary is machine-generated.

The DocMemo platform effectively recruits individuals interested in Alzheimer's disease research. Older age, cognitive complaints, and depression were key factors associated with willingness to participate in studies.

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Area of Science:

  • Neurology
  • Gerontology
  • Digital Health

Background:

  • Recruiting participants for early-stage Alzheimer's disease (AD) research is critical but challenging.
  • DocMemo is a digital platform in France and the US designed for individuals with memory concerns.
  • The platform offers cognitive screening, appointment scheduling, and a pathway for research participation interest.

Purpose of the Study:

  • To evaluate DocMemo's effectiveness in identifying potential research participants for AD studies.
  • To determine the proportion of users willing to be recontacted for research opportunities.
  • To identify factors associated with research participation agreement in France and the US.

Main Methods:

  • Data collected from DocMemo users included demographics, cognitive, psychological, health, and lifestyle information.
  • User agreement to be recontacted for research was recorded (yes/no).
  • Multivariable logistic regressions analyzed factors linked to agreement, with adjustments for multiple comparisons.

Main Results:

  • Over 13,000 unique users interacted with DocMemo across France and the US.
  • 20.09% of French users and 13.09% of US users agreed to be recontacted.
  • Older age, cognitive complaints, and depression were significant predictors of agreement in both countries. French users also showed higher agreement with female gender, high education, and family history of AD.

Conclusions:

  • DocMemo successfully generates a consistent pool of individuals at risk for Alzheimer's disease and related dementias (ADRD) who are interested in research.
  • This digital platform can significantly aid in meeting recruitment demands for multiple simultaneous research studies.
  • DocMemo facilitates timely recruitment, crucial for advancing AD research and interventions.