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Clinical Manifestations.

Davina Kavita Premraj1, Yasmin Soliman2, Carmela Tartaglia3

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Summary
This summary is machine-generated.

Older women show more persistent concussion symptoms than men, with dementia being more common in those over 65. Further research is needed to understand concussion

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Area of Science:

  • Neurology
  • Gerontology
  • Cognitive Science

Background:

  • Falls and concussions are increasing concerns in aging populations.
  • Older adults with concussions are often misdiagnosed with mild cognitive impairment (MCI) or dementia.
  • Sex differences in cognitive presentation after concussion require further investigation.

Purpose of the Study:

  • To investigate sex differences in cognitive presentation following concussion in older adults.
  • To analyze the prevalence of normal cognition, MCI, and dementia in older adults post-concussion.
  • To identify potential sex-based disparities in concussion outcomes.

Main Methods:

  • Retrospective study of patients over 50 with concussion at Toronto Western Hospital (last 3 years).
  • Data collected via REDCap, including demographics, diagnoses, and Toronto Cognitive Assessment (TorCA).
  • Patients categorized by sex and cognitive status (Normal, MCI, Dementia) based on TorCA scores, MCI probability, and age.

Main Results:

  • More females (n=50) than males (n=26) presented with concussion within three years.
  • Fewer females (6%) had MCI compared to males (21%), though not statistically significant (p=0.12).
  • Dementia prevalence was similar between sexes (females 35%, males 38%) and higher in adults aged 65+ (48.15%).

Conclusions:

  • Females exhibit a higher prevalence of persistent concussion symptoms than males in older adults.
  • Dementia is more frequent in older individuals (65+) compared to younger ones (50-64).
  • Further research is needed to clarify concussion's role in MCI and dementia diagnoses.