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Clinical Manifestations.

Fabiana Carla Matos da Cunha Cintra1, Marco Túlio Cintra1, Gerson Santos Azevedo1

  • 1Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
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Summary
This summary is machine-generated.

Long COVID can lead to cognitive impairment and functional disability in the elderly. This study found a significant correlation between cognitive and functional issues in older adults post-COVID-19 infection.

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Area of Science:

  • Gerontology
  • Infectious Diseases
  • Neurology

Background:

  • COVID-19 is linked to long-term cognitive impairment (CI) and functional disability (FI).
  • Elderly individuals are particularly vulnerable to these post-COVID-19 effects.
  • Understanding the relationship between CI and FI is crucial for managing long-term health outcomes.

Purpose of the Study:

  • To investigate the correlation between cognitive impairment and functional disability in elderly individuals following a COVID-19 diagnosis.
  • To identify specific cognitive and functional deficits experienced by older adults post-COVID-19.

Main Methods:

  • A cross-sectional study nested within a prospective cohort of elderly individuals and their caregivers post-COVID-19 diagnosis.
  • Cognition assessed using the Z-score of the Dementia Rating Scale.
  • Functionality measured by the Functional Independence Measure (FIM) and its subitems.

Main Results:

  • 80 elderly participants (mean age 73.91 years) were evaluated a mean of 10 months post-infection.
  • 54.43% experienced cognitive disability, and 92% showed a correlation between cognitive impairment and functional disability (p=0.008).
  • Weak correlations were observed between cognitive impairment and overall FIM scores, as well as specific items like memory, social interaction, and transfers.

Conclusions:

  • A significant relationship exists between cognitive impairment and functional disability in the elderly after COVID-19.
  • Findings highlight the need for targeted prevention and rehabilitation strategies for this population.
  • Improved understanding can enhance the health and care for elderly individuals and their caregivers.