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FedRS: Federated Learning Under Reliable Supervision for Multi-Organ Segmentation With Inconsistent Labels
IEEE Transactions on Medical Imaging
|December 26, 2025
Summary
Federated Learning under Reliable Supervision (FedRS) addresses inconsistent medical image labels in decentralized training. This method improves multi-organ segmentation accuracy and reduces communication costs for better generalization.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Computer Vision
Background:
- Multi-organ segmentation typically requires large, fully labeled datasets.
- Medical image data is often decentralized due to privacy concerns and partially labeled due to high annotation costs, leading to label inconsistency.
- Federated learning enables privacy-preserving decentralized training but struggles with label inconsistency, causing model divergence.
Purpose of the Study:
- To propose an effective and communication-efficient federated learning method for multi-organ segmentation.
- To address the challenge of label inconsistency in decentralized medical image datasets.
- To improve the accuracy and generalization capability of federated learning models in medical image segmentation.
Main Methods:
- Developed Federated Learning under Reliable Supervision (FedRS) with Less-Forgetting and Less-Constraint loss functions to reduce local model divergence.
- Implemented a global model aggregation strategy based on prediction consistency between local and global models.
- Utilized a lightweight model backbone (4.1M parameters) to minimize communication costs.
Main Results:
- FedRS demonstrated superior performance compared to localized, centralized, and state-of-the-art federated learning methods on nine public 3D abdominal CT datasets.
- The method achieved strong effectiveness and generalization capabilities on both in-federation and out-of-federation datasets.
- FedRS significantly reduced communication costs due to its efficient model architecture.
Conclusions:
- FedRS effectively handles label inconsistency in federated medical image segmentation.
- The proposed method enhances global model reliability and achieves state-of-the-art performance.
- FedRS offers a communication-efficient solution for decentralized medical image analysis.

