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Retractions of Health Economic Evaluations: A Systematic Review
Eric Julian Manalastas1, Aditi Hombali2, Juliette C Thompson2
1Visible Analytics, Prama House, 267 Banbury Road, Oxford, OX2 7HT, UK. eric.manalastas@visibleanalytics.co.uk.
Pharmacoeconomics - Open
|December 26, 2025
Summary
Retracted health economic evaluations are increasing, driven by errors and misconduct. Despite retractions, some studies remain influential in reviews and clinical practice.
Area of Science:
- Health Economics
- Scientific Integrity
- Publication Ethics
Background:
- Scientific article retractions have risen across health fields.
- The impact of retractions on health economic evaluations remains unclear.
- This study addresses the gap in understanding retracted health economic evaluations.
Purpose of the Study:
- Identify retracted health economic evaluations.
- Characterize these retracted studies.
- Analyze the reasons behind their retraction.
Main Methods:
- Systematic review of retracted health economic evaluations.
- Databases searched: MEDLINE, Embase, Retraction Watch.
- Analysis of retraction notices for publication details and reasons.
Main Results:
- 17 retracted economic evaluations identified (2006-2024).
- Errors (64%) and misconduct (24%) were primary reasons for retraction.
- Despite retraction, 35% were cited in reviews, and 6% informed practice.
Conclusions:
- Retractions of health economic evaluations are occurring due to errors and misconduct.
- Retracted studies can continue to be cited and influence practice.
- Further scrutiny of economic evaluations is warranted.
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