Related Experiment Video
Updated: Jan 7, 2026

04:56
Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm
Published on: August 1, 2025
442
A 15-Year Single-Center Experience Treating Complex Aortic Aneurysms: Transitioning From Open to Complex Endovascular
B W C M Warmerdam1, J Hjortnaes1, A H G Driessen2
1Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Summary
Complex endovascular aortic repair (EVAR) treats more complex aneurysms in frailer patients. While less invasive, complex EVAR carries risks, especially for the frailest, necessitating refined patient selection for optimal outcomes.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Aneurysm Treatment
Background:
- Complex aortic aneurysms present significant treatment challenges.
- The introduction of complex endovascular aortic repair (EVAR) alongside open surgical repair (OSR) has altered treatment paradigms.
- Tertiary referral centers manage a diverse range of complex aneurysm cases.
Purpose of the Study:
- To analyze real-world clinical profiles and surgical outcomes of complex (thoraco-)abdominal aneurysm patients.
- To evaluate the current decision-making process for surgical versus endovascular repair.
- To assess outcomes based on patient frailty and treatment modality.
Main Methods:
- Retrospective analysis of patients undergoing OSR and complex EVAR (2008-2023).
- Analysis of treatment decision rationale and patient characteristics.
- Subanalysis of frailest complex EVAR patients deemed unfit for OSR.
Main Results:
- 112 OSR and 119 complex EVAR patients were included; patient preference often guided shared decision-making.
- Complex EVAR patients had higher comorbidity scores (Charlson Comorbidity Index).
- OSR had more complications (31.3%), while complex EVAR had more reinterventions (20.2%).
- Frailest complex EVAR patients (n=47) showed lower survival and high 1-year mortality (23.8%).
Conclusions:
- Complex EVAR, while less complicated than OSR, involves significant risks, particularly for frail patients.
- Current selection processes identify frail patients for complex EVAR but may not optimize non-surgical management candidates.
- Further insights into patient selection are crucial for improving outcomes in complex aneurysm treatment.
Related Concept Videos
Aneurysm III: Interprofessional Care
233
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
233
Aortic Regurgitation III: Medical Management
359
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
359

