Ultrasound for the assessment of muscle architecture in Parkinson's disease: A scoping review
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View abstract on PubMed
Summary
This summary is machine-generated.Parkinson's disease impairs muscle responsiveness, though resting muscle architecture is mostly preserved. Ultrasound imaging reveals these changes, highlighting the need for standardized protocols to understand muscle structure and function in PD.
Area Of Science
- Neurology
- Biomedical Engineering
- Musculoskeletal Imaging
Background
- Parkinson's disease (PD) significantly impacts motor function and muscle performance.
- Muscle architecture (MA) is intrinsically linked to motor control.
- Ultrasound (US) offers a non-invasive approach to assess MA, but its use in PD research is limited.
Purpose Of The Study
- To systematically review and synthesize existing research on the use of ultrasound (US) to assess muscle architecture (MA) in individuals with Parkinson's disease (PD).
- To clarify how US imaging methodologies can elucidate muscle structure and function in the context of PD.
Main Methods
- A comprehensive scoping review methodology was employed.
- Extensive literature searches were conducted across major scientific databases: Scopus, PubMed, Web of Science Core Collection, MEDLINE, and CINAHL Ultimate.
- Twenty studies met the inclusion criteria from an initial pool of 913 identified records.
Main Results
- While resting muscle architecture (MA) in PD is generally preserved, muscle fascicle responsiveness during contraction is notably impaired, potentially due to rigidity.
- Observed MA differences correlate with PD clinical manifestations like bradykinesia and rigidity, and with reduced functional performance.
- Comorbidities such as sarcopenia and dysphagia exacerbate MA degradation in PD patients. Exercise interventions demonstrated potential to positively alter MA characteristics.
Conclusions
- Consistent evidence indicates altered MA and impaired muscle responsiveness in PD.
- Methodological heterogeneity and small sample sizes in current research limit definitive conclusions.
- Standardized US protocols and longitudinal studies are crucial for clarifying the relationship between MA, functional performance, and PD, and for evaluating rehabilitation efficacy.
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