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Related Experiment Video

Updated: Jan 7, 2026

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Increasing Colorectal Cancer Screening: A Systematic Economic Review of Patient Navigation Services.

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Patient navigation services are a cost-effective strategy to increase colorectal cancer (CRC) screening rates and reduce health disparities. These services show a favorable return on investment (ROI) for colonoscopies, making them economically viable.

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Area of Science:

  • Health Economics
  • Public Health
  • Cancer Prevention

Background:

  • Colorectal cancer (CRC) screening rates remain suboptimal, particularly in vulnerable populations.
  • Disparities in CRC screening contribute to unequal health outcomes.
  • Patient navigation (PN) services have emerged as a potential strategy to address these challenges.

Purpose of the Study:

  • To systematically review the economic evidence of patient navigation (PN) services for increasing colorectal cancer (CRC) screening.
  • To evaluate the cost-effectiveness and return on investment (ROI) of PN services in reducing CRC screening disparities.

Main Methods:

  • Systematic economic review of English-language studies from high-income countries (database inception to December 2022).
  • Exclusion of studies on patients with existing cancer or without healthcare system involvement.
  • Monetary values reported in 2022 U.S. dollars; data collection and analysis completed in 2023.

Main Results:

  • Seventeen studies were included (16 from the U.S., 1 from France).
  • Median intervention cost per person was $150; median cost per additional person screened was $663.
  • Return on investment (ROI) for colonoscopy was a median of 2.3%; cost per QALY gained was negative, indicating cost savings.

Conclusions:

  • Patient navigation services are cost-effective for increasing CRC screenings, exceeding the $50,000 per QALY gained threshold.
  • PN services demonstrate a favorable ROI for increasing CRC screening via colonoscopy.
  • Economic evidence supports PN services as a valuable tool for improving CRC screening and reducing disparities.