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Updated: Jul 21, 2026

A Polyaniline-based Sensor of Nucleic Acids
Published on: November 1, 2016
Highly conductive and adsorptive nitrogen-doped biochar-based electrochemical sensor for sensitive bisphenol A
Lingzhi He1, Guangjian Liao1, Yadong Yang2
1Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, Hubei Key Laboratory of Material Chemistry and Service Failure, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan, 430074, China.
None:
Herein, a sensitive and cost-effective electrochemical sensor based on bifunctional nitrogen-doped biochar (NBC) was developed for the detection of bisphenol A (BPA). NBC synthesized with urea-modified biomass exhibited enhanced surface area, increased pore volume, and modified electronic density. Adsorption experiments revealed efficient BPA enrichment through synergistic pore-filling effects and π-π electron interactions. Electrochemical characterization demonstrated nitrogen doping-induced structural defects significantly enhanced conductivity. As revealed by density functional theory (DFT) analysis, the amplified bifunctional effects enhanced electrochemical oxidation signals, endowing the 3NBC/GCE sensor with a detection limit of 1.75 nM and a linear response range of 0.005-25 μM while surpassing most metal-based sensors in performance. The sensor also exhibited excellent stability, reproducibility, and interference resistance, successfully detecting BPA in environmental water samples with high-performance liquid chromatography validation. Therefore, the nitrogen-doped biochar holds significant potential for the development of low-cost, robust, and reliable electrochemical sensors for BPA detection.
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