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Updated: Jan 7, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Mental health challenges associated with sickle cell disease and strategies to address them: Reflections from a
Adedotun Adeyokunnu1, Heather Avant2, Steven Hardy3
1Sikcell, Philadelphia, PA 19405, USA.
Abstract:
Despite advances in treatment, the mental health challenges of individuals living with Sickle Cell Disease (SCD) remain critically overlooked. Depression, anxiety, and post-traumatic stress disorder disproportionately affect this population, yet mental health support is often inadequate or absent. This paper presents patient-driven insights into the psychological toll of SCD, emphasizing the urgent need for integrated care approaches that address both physical and mental health. By exploring barriers to mental health access, the impact of medical trauma, and strategies for resilience, we aim to shift the conversation toward a more holistic, patient-centered model of SCD care.
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