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Related Experiment Video

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Rat Model of Adhesive Capsulitis of the Shoulder
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Improving Standards for Embolization of Adhesive Capsulitis.

Ana M Fernández-Martínez1, Marc Sapoval2, Tom Lévy-Boeken2

  • 1Vascular and Interventional Radiology, University Hospital of León, Calle Altos de Nava, 24080, León, SN, Spain. am_fermar@hotmail.com.

Cardiovascular and Interventional Radiology
|December 28, 2025
PubMed
Summary

Transarterial embolization (TAE) offers a minimally invasive treatment for adhesive capsulitis (AC) unresponsive to standard therapies. This review outlines recommendations for adhesive capsulitis embolization (ACE) to standardize practice and improve research consistency.

Keywords:
Adhesive capsulitisEmbolizationImipenem/cilastatin sodiumShoulderStiffness

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Area of Science:

  • Interventional Radiology
  • Musculoskeletal Medicine

Background:

  • Adhesive capsulitis (AC), or frozen shoulder, is a debilitating condition often resistant to conventional treatments.
  • Transarterial embolization (TAE) is emerging as a minimally invasive option targeting the inflammatory and vascular components of AC.
  • Current literature on TAE for AC is heterogeneous, necessitating standardized guidelines.

Purpose of the Study:

  • To provide expert recommendations for performing transarterial embolization for adhesive capsulitis (ACE).
  • To promote standardized techniques and consistent methodologies in future research on ACE.
  • To detail patient selection, technical procedural aspects, and follow-up protocols for ACE.

Main Methods:

  • Systematic review of existing literature on TAE for adhesive capsulitis.
  • Development of evidence-based recommendations for patient selection, arteriography, and embolization techniques.
  • Inclusion of an appendix for standardized data collection in future ACE studies.

Main Results:

  • TAE targets neo-angiogenesis and nerve stimulation to alleviate pain in refractory AC.
  • Early studies suggest promising outcomes for TAE in managing adhesive capsulitis.
  • Standardized protocols are crucial due to heterogeneity in current techniques and outcome assessments.

Conclusions:

  • Adhesive capsulitis embolization (ACE) represents a promising therapeutic avenue for refractory cases.
  • Standardized guidelines are essential for consistent application and reliable evaluation of ACE.
  • This review aims to facilitate reproducible research and improve clinical practice for ACE.