[Yeast biotechnology and green biomanufacturing: current status and future prospects]

Yeasts have a long history of worldwide applications in the production of foods, pharmaceuticals, chemicals, and cosmetics. In recent years, continuous advancements in yeast strain engineering and fermentation technologies, combined with increasing societal emphasis on environmental sustainability and human health, have significantly expanded and deepened the industrial applications of yeast biotechnology. The use of yeasts to produce alternative proteins and cosmetics is emerging as a promising industry trend. Additionally, yeast-based production platforms are increasingly being industrialized for manufacturing biodegradable materials and bioactive compounds with medical and health-promoting properties, highlighting their broad application potential. To ensure a sustainable feedstock supply for yeast biomanufacturing, the use of fermentable sugars derived from renewable biomass, especially the hydrolysate of lignocellulosic renewable biomass, represents a research direction of great significance. This review systematically summarizes the current state of development in yeast-based biotechnology industries and offers a perspective on emerging trends and future prospects for the next generation of yeast-driven industrial processes. This review provides insights into further expanding the industrial applications of yeast, advancing the development of the bioeconomy, and improving the efficiency of green biomanufacturing.