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Updated: Jan 7, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
[Plant synthetic biology technologies and natural product biosynthesis]
Cuihuan Zhao1,2, Jie Wu1,2, Jinlong Qiu1,2
1State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Abstract:
Synthetic biology, as a pivotal frontier in 21st-century life sciences, is accelerating the expansion of engineering principles from unicellular microbes to multicellular higher plants. Plant synthetic biology aims to rationally design and reconstruct complex biological functions through the modular assembly of genetic elements, regulatory components, and metabolic pathways. This review outlines the foundational research landscape and major application directions of plant synthetic biology, with a particular focus on recent advances in synthetic promoters and regulatory elements, precision genome editing technologies, and the design of programmable gene circuits. Moreover, we highlight the transformative potential of plant synthetic biology in natural product biosynthesis. In addition to summarizing technological progress, this article critically examines current challenges facing the field and provides perspectives on future development trends of plant synthetic biology.
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