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Updated: Jan 7, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
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Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

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Losartan attenuates depression-like behavior in epileptic rats by regulating the TGF-β/Smad signaling

Penghui Cao1, Shichuan Shen1, Ziyan Fang2

  • 1Department of Psychiatry, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong 519000, China.

IBRO Neuroscience Reports
|December 29, 2025
PubMed
Abstract

Keywords:
AntidepressantAstrocyte reactivityEpilepsyLosartanTGF-β/ Smad signaling inhibitor

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