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Micropsia and Polyopia Following Multi-Focal Infarction: A Case Report
Tala Allababidi1, Cristina Liberati2,3, Sarasa Tohyama4
1Department of Neurology, Brown University Health, Providence, RI, USA.
The Neurohospitalist
|December 29, 2025
Summary
Alice in Wonderland syndrome (AIWS) can cause visual disturbances like micropsia and polyopia. This case study details a patient with AIWS experiencing these symptoms after a stroke, highlighting a potential common brain network involved.
Area of Science:
- Neuroscience
- Ophthalmology
- Neurology
Background:
- Alice in Wonderland syndrome (AIWS) is characterized by diverse visual perceptual disturbances.
- Common symptoms include altered size perception (micropsia/macropsia), while rarer symptoms like polyopia and kinetopsia also occur.
- Previous neuroimaging studies suggest AIWS involves various, often separate, brain regions.

