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Updated: Jan 7, 2026

Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy
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A Case of Anti-3-Hydroxy-Methylglutaryl-Coenzyme a Reductase (Anti-HMGCR) Immune-Mediated Necrotizing Myopathy

Jennifer S George1, Sahil Sabharwal1, Robert Donnell2

  • 1Internal Medicine, University of Arkansas for Medical Sciences, Fayetteville, USA.

Cureus
|December 29, 2025
PubMed

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Keywords:
anti-hmgcr antibodiesimmune-mediated necrotizing myopathymyositisproximal muscle involvementstatin