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Screening for Diabetes after Solid Organ Transplantation: A 10-Year Retrospective Study
Ridwan B Ibrahim1,2, Sneha Kumar1, Sahil Malik1,2
1Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.
EJIFCC
|December 29, 2025
Summary
Post-transplantation diabetes mellitus (PTDM) screening is crucial for transplant recipients but remains suboptimal. Rates vary significantly by organ type, with lung transplant recipients showing higher screening than kidney, liver, and heart recipients.
Area of Science:
- Transplantation Medicine
- Endocrinology
- Pediatric Nephrology
Background:
- Post-transplantation diabetes mellitus (PTDM) is a significant complication impacting solid organ transplant outcomes.
- PTDM is linked to graft rejection, reduced patient survival, infections, and increased cardiovascular risk.
- Early PTDM detection and management are vital, yet screening rates are often suboptimal despite guidelines.
Purpose of the Study:
- To analyze PTDM screening rates in pediatric solid organ transplant recipients.
- To identify variations in screening rates across different organ types (kidney, liver, heart, lung).
- To highlight the need for improved PTDM screening protocols and education.
Main Methods:
- Retrospective analysis of PTDM screening data.
- Study period: January 2014 - January 2024.
- Population: Pediatric kidney, liver, heart, and lung transplant recipients at a quaternary academic center.
Main Results:
- PTDM screening rates varied widely by organ type.
- Lung transplant recipients had the highest screening rate (91.7%).
- Kidney (19.4%), liver (14.6%), and heart (34.3%) transplant recipients had lower-than-expected screening rates.
Conclusions:
- Suboptimal PTDM screening exists in high-risk pediatric kidney, liver, and heart transplant populations.
- There is a clear need to enhance post-transplantation screening protocols.
- Improved provider education on PTDM screening is essential for better patient outcomes.
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