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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
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  1. Home
  2. Prevalence, Incidence, And Outcome Of Tuberculosis Among Young Hospitalised Children With Acute Illness In Sub-saharan Africa And South East Asia.
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  2. Prevalence, Incidence, And Outcome Of Tuberculosis Among Young Hospitalised Children With Acute Illness In Sub-saharan Africa And South East Asia.

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Prevalence, incidence, and outcome of tuberculosis among young hospitalised children with acute illness in

Mohammod Jobayer Chisti1,2, Ezekiel Mupere2,3, Abu Sadat Mohammad Sayeem Bin Shahid1,2

  • 1International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b) Dhaka, Bangladesh.

Journal of Global Health
|December 29, 2025

View abstract on PubMed

Summary
This summary is machine-generated.

Tuberculosis (TB) affects one in 10 hospitalized children in TB-endemic areas. Clinically diagnosed TB in children increases malnutrition risk and hinders growth post-hospitalization, necessitating ongoing monitoring.

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Area of Science:

  • Pediatric infectious diseases
  • Global health
  • Epidemiology

Background:

  • Tuberculosis (TB) is a major cause of severe illness, mortality, and morbidity in children globally.
  • Identifying TB prevalence in hospitalized children and post-discharge outcomes is crucial in high-burden settings.

Purpose of the Study:

  • To determine the prevalence of TB among severely ill hospitalized children.
  • To document TB incidence, survival, and growth in the six months following hospital discharge in Bangladesh and Uganda.

Main Methods:

  • Children aged 2-23 months in Bangladesh and Uganda were evaluated for TB.
  • Diagnostic evaluation included sputum testing and clinical assessment; children were followed for six months post-discharge.
  • TB classification included bacteriologically confirmed, clinically diagnosed, and unlikely TB.

Main Results:

  • Of 365 children, 17 (4.7%) had confirmed TB, and 46 (12%) had clinically diagnosed TB.
  • 37 children required TB treatment, with half initiated post-discharge.
  • Children with clinically diagnosed TB showed poorer growth trajectories post-discharge compared to those with unlikely TB.

Conclusions:

  • Approximately 1 in 10 hospitalized children in these TB-endemic countries needed TB treatment.
  • Children with clinically diagnosed TB face increased malnutrition and growth deficits post-hospitalization.
  • Post-discharge monitoring for both TB and growth is essential for hospitalized children in TB-endemic regions.