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Management of cardiometabolic risk factors in cardiovascular high-risk populations with varying cognitive levels
Ting Shen1, Meiqi Zhao1, Siyuan Qiao2
1Department of Cardiology, Beijing Anzhen Hospital, National Clinical Research Center for Cardiovascular Diseases, No.2 Anzhen Rd, Chaoyang District, Beijing, 100029, China.
Insights
Cognitive impairment is linked to poorer cardiovascular risk management, especially uncontrolled blood glucose in diabetic patients. This highlights the need for targeted interventions for individuals with cognitive challenges and cardiovascular disease.
Area of Science:
- Cardiology
- Neurology
- Public Health
Background:
- Cognitive impairment can significantly impede effective self-management of cardiovascular disease (CVD).
- This can lead to the worsening of cardiovascular risk factors and poorer health outcomes.
- Understanding the relationship between cognitive function and CVD risk factor control is crucial for patient care.
Purpose of the Study:
- To determine the prevalence of uncontrolled blood pressure, blood lipids, and blood glucose in CVD patients with varying cognitive function levels.
- To identify specific patient groups that require priority for risk factor management.
- To analyze the association between cognitive status and the control of key cardiovascular risk factors.
Main Methods:
- A cross-sectional study involving 10,707 patients with CVD or high cardiovascular risk.
- Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) scale, categorizing participants into normal (MoCA ≥ 26) or impaired (MoCA < 26) groups.
- Logistic regression analysis was employed to examine the relationship between cognitive function and uncontrolled risk factors.
Main Results:
- Diabetic patients with cognitive impairment showed significantly higher rates of uncontrolled blood glucose (hemoglobin A1c ≥ 7%: 65.7% vs. 56.6%).
- While rates of uncontrolled blood pressure and lipids were slightly higher in those with cognitive impairment, these differences were not statistically significant.
- The adjusted odds ratio for uncontrolled blood glucose in cognitively impaired diabetic patients was 1.40 (95% CI: 1.21-1.62).
Conclusions:
- Cognitive impairment is significantly associated with an unfavorable cardiovascular risk profile in patients with CVD.
- These findings suggest potential self-management challenges faced by patients with cognitive impairment.
- Proactive and tailored care strategies are essential for managing cardiovascular risk in this population.
Background:
Cognitive impairment may hinder effective self-management of cardiovascular disease and lead to worsening cardiovascular risk.
Aims:
This study aimed to describe the rate of uncontrolled blood pressure, blood lipids, and blood glucose across different cognitive levels to identify priority groups for managing risk factors in patients with cardiovascular disease.
Methods:
A total of 10,707 patients with cardiovascular disease or individuals at high cardiovascular risk were enrolled from Beijing Anzhen Hospital. Cognitive function, assessed using the Montreal Cognitive Assessment (MoCA) scale, was categorized as normal (MoCA ≥ 26) or impaired (MoCA < 26). Logistic regression was used to explore the association between cognitive function and the rates of uncontrolled blood pressure, lipids, and glucose.
Results:
Among diabetic patients, the rate of uncontrolled blood glucose in those with cognitive impairment was significantly higher in patients with cognitive impairment than in those with normal cognition [hemoglobin A1c ≥ 7%, 65.7% vs. 56.6%, adjusted odds ratio (aOR) (95% confidence interval, 95% CI):1.40(1.21-1.62), P < 0.001]. The rate of uncontrolled blood pressure and blood lipids were slightly higher in cognitive impairment than normal cognition, however, the differences were not statistically significant [systolic blood pressure(SBP) ≥ 130mmHg and/or diastolic blood pressure(DBP) ≥ 80mmHg, 74.6% vs. 70.5%, aOR(95% CI):1.07 (0.96-1.20), P = 0.206; SBP ≥ 140mmHg and/or DBP ≥ 90mmHg, 45.4% vs. 40.0%, aOR(95% CI):1.08(0.98-1.91), P = 0.125; poor blood lipids management, 72.2% vs. 70.5%, aOR (95% CI):1.00(0.89-1.13), P = 0.994].
Conclusions:
In this cross-sectional study, a significant association was observed between cognitive impairment and an unfavorable cardiovascular risk profile. This may reflect challenges in self-management and underscores the need for proactive care.
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