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Phenotype, Management, and Outcomes in Paediatric Acute Pancreatitis: A Real-Life Cross-Sectional Study
Catherine Korman1,2, Doha Elhaoua1,3, Sarah Blain1,4
1CHU Sainte-Justine Research Centre, Montréal, Canada.
Acta Paediatrica (Oslo, Norway : 1992)
|December 29, 2025
Summary
This study analyzed pediatric acute pancreatitis cases, finding diverse causes like medications and biliary disease. Management aligned with guidelines, but no severe cases occurred, suggesting a need for better severity prediction in children.
Area of Science:
- Pediatric Gastroenterology
- Clinical Epidemiology
Background:
- Limited Canadian data exists on pediatric acute pancreatitis.
- North American studies report severe acute pancreatitis rates around 13.7%.
- Guidelines emphasize fluid management and early enteral nutrition.
Purpose of the Study:
- To evaluate the epidemiology of pediatric acute pancreatitis.
- To assess the management strategies for acute pancreatitis in children at a tertiary care center.
Main Methods:
- Retrospective analysis of a hospital database.
- Inclusion of pediatric patients diagnosed with acute pancreatitis between January 2014 and December 2021.
- Descriptive statistical analysis using SAS software.
Main Results:
- 208 pediatric patients diagnosed with acute pancreatitis.
- Most common etiologies: medication (20.2%), biliary disease (16.4%), infections (15.4%).
- 10.6% had moderately severe pancreatitis; no severe cases were reported. Most patients received IV fluids; initial dietary management varied (enteral nutrition, oral feeding, fasting).
Conclusions:
- Pediatric acute pancreatitis presents with varied etiologies.
- Current management practices align with established pediatric gastroenterology guidelines.
- Further research is needed to identify predictive factors for pancreatitis severity in children.
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