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Related Experiment Video

Updated: Jan 7, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
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Maternal Racial Differences and Socioeconomic Status in Preterm Infant Neurodevelopment, Feeding, and Growth.

Tingting Zhao, Aolan Li, Weizi Wu

    Nursing Research
    |December 29, 2025
    PubMed
    Summary
    This summary is machine-generated.

    Maternal racial disparity and socioeconomic status (SES) significantly impact preterm infant feeding, growth, and neurodevelopment. Addressing these disparities is crucial for improving long-term health outcomes in vulnerable newborns.

    Keywords:
    ZIP codefeedinggrowthneurodevelopmentpreterm infantracial disparitysocieconomic status

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    Area of Science:

    • Neonatal Health
    • Pediatric Neurodevelopment
    • Health Disparities Research

    Background:

    • Preterm birth poses risks for infant neurodevelopment and health.
    • Maternal socioeconomic status (SES) is linked to preterm birth, but its predictive role in infant outcomes needs further exploration.
    • Racial disparities in maternal SES may exacerbate these risks.

    Purpose of the Study:

    • To examine the associations between maternal race, ZIP code-level SES, and infant feeding, growth, and neurodevelopmental trajectories.
    • To identify key SES-related risk factors influencing these infant outcomes.

    Main Methods:

    • A cohort study of 181 preterm infants recruited from Connecticut NICUs.
    • Assessment of infant feeding, growth, and neurodevelopment using standardized scales.
    • XGBoost and SHAP values were employed to analyze health outcomes and identify SES-related risk factors.

    Main Results:

    • Infants born to Black mothers exhibited significantly poorer birth metrics (gestational age, weight, length, head circumference) and higher illness severity scores compared to infants of White mothers.
    • Black mothers were younger, less educated, single, and faced higher poverty levels and larger family sizes.
    • Key predictors of infant outcomes included birth weight, gestational age, illness severity, family size, maternal age, income, poverty, and school enrollment.

    Conclusions:

    • Maternal racial disparities and SES are significant predictors of feeding, growth, and neurodevelopmental outcomes in preterm infants.
    • These findings highlight the need for targeted healthcare strategies to support vulnerable preterm populations and improve long-term health.