Treatment with losartan for visual rehabilitation post infectious keratitis: Case report

We report the case of a 56-year-old male patient with mixed infectious keratitis who developed a 5 × 5 mm corneal ulcer with irregular borders and positive fluorescein staining. After topical and systemic treatment, the infectious process resolved. Topical losartan was then initiated to reduce residual fibrosis and support visual rehabilitation. During follow-up, a progressive improvement in visual acuity and a reduction in corneal leucoma were observed. This case highlights the potential of losartan as a therapeutic alternative for managing corneal opacities secondary to inflammatory or infectious processes. Its antifibrotic effect is associated with its ability to penetrate the corneal stroma, modulate fibroblast activity, and inhibit scar tissue formation. In the absence of specific treatments for corneal fibrosis, losartan represents a promising option with relevant clinical implications for preventing vision loss and improving patients' quality of life.