Recognition, Diagnosis, and Management of Measles in the Emergency Department

Danielle K Daniels1, Pranjali Muppidi1, Yasmika Rasakumar1

  • 1Assistant Professor of Pediatrics, Division of Pediatric Infectious Diseases, Department of Pediatrics, Upstate Golisano Children's Hospital, SUNY Upstate Medical UniversitySyracuse, New York.

Pediatric Emergency Care
|December 29, 2025
PubMed

Insights

Measles, a contagious viral illness, is resurging due to vaccine hesitancy, leading to severe outbreaks. This review aids clinicians in diagnosing and managing measles amid growing unfamiliarity with the disease.

Area of Science:

  • * Virology and Epidemiology
  • * Pediatric Infectious Diseases

Background:

  • * Measles (Morbillivirus) is a highly contagious viral infection that caused significant morbidity and mortality before widespread vaccination.
  • * Declared eliminated in the U.S. in 2000, measles continues to circulate globally.
  • * Rising vaccine hesitancy and decreased vaccination rates have led to recent outbreaks of increasing severity.

Purpose of the Study:

  • * To review the epidemiology of measles.
  • * To prepare clinicians to differentiate measles from other febrile exanthems in children.
  • * To outline diagnostic methods and patient management strategies for measles.

Main Methods:

  • * Literature review of measles epidemiology, diagnostics, and management.
  • * Analysis of current trends in measles outbreaks and vaccine hesitancy.
  • * Synthesis of information for clinical application.

Main Results:

  • * Measles outbreaks are increasing in frequency and severity globally.
  • * Clinicians may lack familiarity with measles presentation and management.
  • * Accurate differentiation from other childhood exanthems is crucial.

Conclusions:

  • * Enhanced vigilance and diagnostic capabilities are needed to address resurgent measles.
  • * Clinicians require updated knowledge on measles epidemiology, diagnosis, and management.
  • * Public health strategies must address vaccine hesitancy to prevent future outbreaks.

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