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Incidental appendectomy during laparotomy for idiopathic intussusception in children: a dual-center retrospective
Tao Liu1, Xian-Feng Wei2, Yeerfan Aierken1
1Department of General Surgery, School of Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Insights
Incidental appendectomy during pediatric idiopathic intussusception surgery does not reduce recurrence or complications. This procedure, however, increases operative time and costs, suggesting routine use should be reconsidered.
Area of Science:
- Pediatric Surgery
- Gastroenterology
Background:
- The necessity of incidental appendectomy (IA) in pediatric idiopathic intussusception surgery is debated.
- This study assesses the benefits and risks of performing IA during open reduction for intussusception.
Purpose of the Study:
- To evaluate the impact of incidental appendectomy on perioperative complications and recurrence rates in children with idiopathic intussusception.
- To analyze the effect of IA on operative time, recovery, length of stay, and hospitalization costs.
Main Methods:
- A retrospective cohort study involving 177 children undergoing open reduction for idiopathic intussusception across two centers (2014-2021).
- Patients were categorized based on whether incidental appendectomy was performed.
- Outcomes included perioperative complications, recurrent intussusception, operative time, time to oral intake, length of stay, and cost, analyzed using univariable and multivariable models.
Main Results:
- Incidental appendectomy (IA) was performed in 114 patients; 63 did not undergo IA. Baseline characteristics were similar, though non-IA patients had more air enema attempts and a higher rate of ileocolic intussusception.
- No significant differences were observed in perioperative complications (11.4% vs. 14.3%) or recurrent intussusception (6.1% vs. 11.1%) between the IA and non-IA groups.
- IA was associated with significantly longer operative times (P=0.016) and increased total hospitalization costs (P<0.001), with no significant impact on postoperative oral intake or length of stay.
Conclusions:
- Incidental appendectomy in pediatric idiopathic intussusception does not improve outcomes regarding recurrence or perioperative complications.
- The procedure leads to extended surgical duration and higher healthcare costs, with most removed appendices showing minimal inflammation.
- Routine incidental appendectomy in this context warrants reconsideration, and further prospective studies are recommended to guide surgical practice.
Background:
The role of incidental appendectomy (IA) during surgery for idiopathic intussusception in children remains controversial. This study evaluated the potential benefits and risks of performing IA during laparotomy.
Methods:
We performed a dual-center retrospective cohort study of children who underwent open reduction for idiopathic intussusception (2014-2021). Patients were grouped by whether IA was performed. Primary outcomes were perioperative complications (PCs) and recurrent intussusception (RI); secondary outcomes were operative time, time to postoperative oral intake (PO time), length of stay (LOS), and hospitalization cost. Univariable and multivariable analyses were applied, with subgroup analysis for ileocolic cases.
Results:
A total of 177 children were included, of whom 114 underwent IA and 63 did not. Baseline demographics were similar, but non-IA patients had more air enema attempts (median 2 vs. 1; P < 0.001) and a higher proportion of ileocolic intussusception (85.7% vs. 69.3%; P < 0.001). Intraoperatively, red or swollen appendices were more frequently removed (86.0% vs. 3.2%). Histopathology revealed acute inflammation in 60%, chronic inflammation in 25%, and no abnormalities in 15%. Rates of PCs (11.4% vs. 14.3%) and RI (6.1% vs. 11.1%) did not differ significantly between groups. In adjusted analyses, IA was associated with longer operative time (exp(β) = 1.292, 95% CI: 1.048 - 1.593; P = 0.016) and higher total costs (exp(β) = 1.350, 95% CI: 1.176 - 1.550; P < 0.001), without significant effects on PO time or LOS. Subgroup analysis of ileocolic cases (n = 133) yielded consistent results.
Conclusions:
In pediatric idiopathic intussusception, IA did not decrease recurrence or perioperative complications but prolonged surgery and increased costs. As most resected appendices showed only minor inflammatory changes, routine IA should be reconsidered. Prospective multicenter studies are needed to validate these findings and guide surgical decision-making.
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