Risk Factors and Clinical Outcomes of Post-Extubation Stridor in Pediatric Intensive Care
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View abstract on PubMed
Summary
This summary is machine-generated.Pediatric post-extubation stridor is common, with risk factors including intubation outside specialized centers and prolonged intubation. Stridor is linked to worse outcomes like longer PICU stays and increased extubation failure.
Area Of Science
- Pediatric Critical Care Medicine
- Pediatric Respiratory Medicine
- Intensive Care Unit Management
Background
- Post-extubation stridor is a significant complication in pediatric intensive care units (PICUs).
- Identifying risk factors and clinical outcomes associated with pediatric post-extubation stridor is crucial for improving patient management.
Purpose Of The Study
- To assess risk factors for post-extubation stridor in children.
- To evaluate the impact of post-extubation stridor on clinical outcomes in pediatric patients.
Main Methods
- Prospective cohort study involving 239 children aged 0–13 years undergoing orotracheal intubation in PICUs.
- Data collected included patient characteristics, comorbidities, airway manipulation history, and intubation-related factors.
- Logistic regression analysis identified risk factors; outcomes analyzed until hospital discharge, death, or referral.
Main Results
- Post-extubation stridor occurred in 57.3% of children.
- Risk factors identified: intubation in prehospital/non-specialized hospitals, intubation trauma/complications, and orotracheal intubation >7 days.
- Stridor associated with longer PICU stay, prolonged mechanical ventilation, higher non-invasive ventilation use, increased extubation failure, and cardiorespiratory arrest.
Conclusions
- Intubation in non-specialized settings, prolonged intubation (>7 days), and intubation-related trauma are key risk factors for pediatric post-extubation stridor.
- Children with stridor experience poorer prognoses, including extended PICU and mechanical ventilation durations, and higher extubation failure rates.
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