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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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Disrupted Vessels-Connected Voices: Why Patient Partnership and Cross-Disease Collaboration Are Essential for

Irina Kruetzner1, Freya Droege2, Simone Kesten3

  • 1Working Group Biomedicine and Cellular Biomechanics, Unit of Molecular Biology, Department of Engineering and Natural Sciences, Campus Recklinghausen, Westphalian University of Applied Sciences Gelsenkirchen, Bocholt, Recklinghausen, August-Schmidt-Ring 10, 45665 Recklinghausen, Germany.

Biomedicines
|December 30, 2025
PubMed
Summary

Patient partnerships and cross-disease research are key to advancing therapies for rare vascular diseases like hereditary haemorrhagic telangiectasia (HHT). Collaboration accelerates progress by sharing resources and insights across related conditions.

Keywords:
ALK1BMPCCMHHTMorbus OslerTGF-βendoglinendothelial cellsvascular malformations

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