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Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
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German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
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  2. Research Domains
  3. Agricultural, Veterinary And Food Sciences
  4. Veterinary Sciences
  5. Veterinary Medicine (excl. Urology)
  6. Diagnostic Imaging Of The Skeletal System: Overview Of Applications In Human And Veterinary Medicine

Diagnostic Imaging of the Skeletal System: Overview of Applications in Human and Veterinary Medicine

Ana Javor1, Nikola Štoković2, Natalia Ivanjko2

  • 1Department of Radiology, Ultrasound Diagnostics and Physical Therapy, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia.

Bioengineering (Basel, Switzerland)
|December 30, 2025

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Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound
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A Novel Application of Musculoskeletal Ultrasound Imaging
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View abstract on PubMed

Summary
This summary is machine-generated.

Radiological imaging is vital for diagnosing skeletal disorders in humans and animals. Choosing the right imaging technique, like micro-CT for bone research, requires careful consideration of various factors.

Area of Science:

  • Radiology
  • Orthopedics
  • Biomedical Imaging

Background:

  • Radiological imaging is essential for diagnosing and monitoring skeletal system disorders in both human and veterinary medicine.
  • Various modalities, including radiography, CT, MRI, and ultrasound, are used in clinical practice and research.
  • Advanced techniques like micro-CT and nano-CT enable detailed 3D bone microarchitecture analysis in preclinical studies.

Purpose of the Study:

  • To provide a comprehensive overview of radiological modalities for skeletal system assessment.
  • To critically compare the applications of these modalities in human and veterinary medicine.
  • To highlight the role of emerging technologies like AI in radiological diagnostics.

Main Methods:

  • Review of conventional radiography, DXA, CT, MRI, US, QUS, PET-CT, micro-CT, and nano-CT.
Keywords:
PET CTcomputed tomographydual-energy X-raymagnetic resonance

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  • Comparison of modality applications across human and veterinary clinical practice and research.
  • Discussion on factors influencing modality selection and the integration of AI.
  • Main Results:

    • Radiological imaging is crucial for skeletal health diagnosis, monitoring, and research.
    • Micro-CT and nano-CT offer advanced 3D quantification of bone microarchitecture for preclinical research.
    • AI integration enhances image interpretation, diagnostics, and disease tracking.

    Conclusions:

    • The selection of radiological modalities must be tailored to clinical needs, species, age, and anatomical region, considering practical constraints.
    • Radiation dose, cost, and availability are critical factors, especially in remote settings.
    • Human expertise from clinicians and radiologists remains indispensable for accurate diagnostic imaging.
    micro-CT
    nano-CT
    quantitative ultrasound
    radiography
    skeletal system