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Updated: Jan 7, 2026

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Corneal Tissue Engineering: An In Vitro Model of the Stromal-nerve Interactions of the Human Cornea
Published on: January 24, 2018
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Artificial Intelligence Application in Cornea and External Diseases.
Te-Chen Lu1, Chun-Hao Huang2, I-Chan Lin2,3
1School of Medicine, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Diagnostics (Basel, Switzerland)
|December 30, 2025
Summary
Artificial intelligence (AI) shows high accuracy in detecting various corneal diseases, aiding early diagnosis and management. AI tools also support image analysis, education, and patient monitoring for better eye care.
Area of Science:
- Ophthalmology
- Medical Imaging
- Artificial Intelligence
Background:
- Corneal diseases are a major cause of global blindness.
- Early detection is difficult due to subtle clinical signs.
- Artificial intelligence (AI) offers potential for improved diagnosis of anterior segment disorders.
Purpose of the Study:
- To review current applications of AI in detecting corneal conditions.
- To assess the diagnostic performance of AI models for corneal diseases.
- To explore AI's role in image labeling, education, and patient monitoring.
Main Methods:
- Narrative review of AI applications in corneal disease detection.
- Analysis of AI model performance on test datasets.
- Inclusion of conditions like keratoconus, dry eye, infectious keratitis, pterygium, Fuchs endothelial corneal dystrophy, and corneal transplantation.
Main Results:
- AI models demonstrate high accuracy in detecting corneal conditions, often matching or surpassing junior ophthalmologists.
- AI applications extend to automated image labeling and educational support.
- AI facilitates patient home monitoring for corneal health.
Conclusions:
- AI holds significant potential for enhancing early detection and standardized classification of corneal diseases.
- AI can improve clinical practice and support patient self-care in ophthalmology.
- AI integration promises advancements in managing corneal pathologies and preventing blindness.
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