Somatic Psychoeducational Intervention Is Associated with Increased Oxytocin Levels, Improved Autonomic Function, and...

Background/Objectives. Medical and social care professionals (MSCPs) are disproportionately affected by chronic occupational stress, placing them at elevated risk for autonomic dysregulation, affective disorders, and burnout. Method. This preliminary study includes data obtained from two samples. The data protocols were approved by University of Florida's IRB (IRB202200233 approved 24 February 2023 and IRB202401217 approved on 2 October 2024) and registered at ClinicalTrials.gov (NCT05766852 and NCT06580119). With a total sample of 39 female MSCPs, we investigated the effects of the novel Somatic Psychoeducational Intervention (SPI), grounded in Polyvagal Theory, on autonomic reactivity, psychological distress symptoms, and salivary oxytocin levels. Participants engaged in a three- to four-week intervention integrating psychoeducation, interoceptive training, breathwork, and somatic movement. A subset was randomly assigned via a random number generator to allow for comparison of the intervention group (n = 8) to control group (n = 7). Results. Repeated measures ANOVA revealed increases in salivary oxytocin (η_p² = 0.46) and reductions in autonomic reactivity (η_p² = 0.24) and psychological distress symptoms (η_p² ranging from 0.24 to 0.47). Benefits were sustained at one-month follow-up. Subset analyses focused on participants receiving the intervention at the same time found that only the participants in the intervention group improved with regard to autonomic reactivity and symptoms of anxiety and depression. Correlational analyses showed that changes in oxytocin and autonomic reactivity were associated with mindfulness improvements, which in turn predicted symptom reduction. Conclusions. These preliminary findings support SPI as a potentially scalable intervention with neurophysiological and psychological benefits. However, high attrition and small subgroup sizes necessitate cautious interpretation.