Related Experiment Video
Updated: Jan 7, 2026
Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging
Published on: June 21, 2024
Correlations Between Oxygen Consumption, Ventilatory Mechanics, and Lung Ultrasound in Individuals with Post-COVID
Jéssica Gabriela Messias Oliveira1, Samantha Gomes de Alegria1, Isabelle da Nóbrega Ferreira1
1Post-Graduation Programme in Medical Sciences, School of Medical Sciences, Universidade do Estado do Rio de Janeiro (UERJ), Avenida Professor Manoel de Abreu, 444, 2º andar, Vila Isabel, Rio de Janeiro 20550-170, Brazil.
Introduction:
Since COVID-19 primarily targets the respiratory system, it is essential to longitudinally monitor functional capacity and pulmonary function in individuals with post-COVID syndrome (PCS). This study aimed to evaluate the functional capacity of individuals with PCS during exercise using cardiopulmonary exercise testing (CPX) and examine its association with spirometry, impulse oscillometry (IOS), and lung ultrasound (LUS) parameters.
Methods:
Sixty individuals participated in this study. We assessed CPX, which measured peak oxygen consumption (VO2peak), in addition to IOS, spirometry, and LUS.
Results:
The mean VO2peak was 18.4 ± 5.9 mL/kg/min. Significant negative correlations were found between VO2peak and the following parameters: age (rs = -0.465, p = 0.0002), body mass index (BMI, rs = -0.354, p = 0.0056), resonance frequency using IOS (rs = -0.312, p = 0.0193), and LUS aeration score (rs = -0.261, p = 0.0439).
Conclusions:
Patients with PCS undergoing CPX demonstrated impaired functional capacity. In these individuals, higher age and BMI were associated with lower VO2peak. Furthermore, alterations in LUS and IOS may also be linked to reduced VO2peak. These findings are promising, as they were obtained using a low-cost device. Further studies are needed to investigate the factors that influence oxygen consumption in PCS.
More Related Videos
08:44Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
Published on: February 2, 2024
08:35Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
Published on: August 17, 2022
Related Concept Videos
01:19Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
01:29Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
01:24Respiratory Capacities
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...
01:25Pulmonary Function Tests
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
01:20Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation: