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Combined Laparoscopic-Robotic Partial Nephrectomy: A Comparative Analysis of Technical Efficiency and Safety
Irfan Safak Barlas1, Mehmet Yilmaz2, Halil Cagri Aybal3
1Department of Urology, Acibadem Ankara Hospital, 06450 Ankara, Turkey.
Journal of Clinical Medicine
|December 30, 2025
Summary
This study shows that a combined partial nephrectomy (CPN) approach, integrating laparoscopic and robotic surgery, is feasible and safe for clinical stage 1 renal tumors. CPN offers comparable oncological and functional outcomes with improved operative efficiency and perioperative results compared to traditional methods.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Surgical Oncology
Background:
- Partial nephrectomy is the standard for clinical stage 1 renal tumors.
- Integrating laparoscopic and robotic techniques offers potential advantages in surgical precision and efficiency.
Purpose of the Study:
- To evaluate the feasibility and safety of a combined partial nephrectomy (CPN) approach.
- To compare perioperative and postoperative outcomes of CPN with traditional laparoscopic (LPN) and robot-assisted partial nephrectomy (RAPN).
Main Methods:
- Retrospective analysis of 99 patients with clinical stage 1 renal tumors.
- Patients underwent LPN (n=31), RAPN (n=16), or CPN (n=52).
- CPN involved laparoscopic mobilization followed by robotic tumor resection and suturing.
Main Results:
- No significant demographic differences between groups.
- CPN demonstrated comparable operative time to LPN and shorter time than RAPN.
- Warm ischemia time and estimated blood loss for CPN were similar to RAPN and better than LPN.
- No major complications (Clavien-Dindo grade ≥3) were observed in any group.
Conclusions:
- Combined partial nephrectomy (CPN) is a feasible and safe surgical approach for clinical stage 1 renal tumors.
- CPN leverages the benefits of both laparoscopic and robotic surgery, offering efficiency and precision.
- CPN achieves comparable oncological and functional results with improved perioperative parameters compared to LPN and RAPN.

