Related Experiment Video

Updated: Jan 7, 2026

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation
06:59

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation

Published on: June 3, 2018

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Effects of Contrast Media on Renal Function Following Computed Tomography Prior to Transcatheter Aortic Valve

Edward Itelman1,2, Jenan Awesat1,2, Pablo Codner1,2

  • 1Cardiology Department, Rabin Medical Center, Petah Tikva 4941492, Israel.

Journal of Clinical Medicine
|December 30, 2025
PubMed

Insights

Contrast-induced (CI) acute kidney injury is uncommon after pre-Transcatheter Aortic Valve Implantation (TAVI) computed tomography (CT) scans, even in patients with chronic kidney disease. Most cases were mild and did not require dialysis, suggesting CT is generally safe.

Area of Science:

  • Cardiology
  • Nephrology
  • Radiology

Background:

  • Preprocedural contrast-enhanced computed tomography (CT) is crucial for Transcatheter Aortic Valve Implantation (TAVI) planning.
  • Concerns exist regarding contrast-induced (CI) acute kidney injury (AKI), particularly in patients with chronic kidney disease (CKD).

Purpose of the Study:

  • To evaluate the incidence of CI-AKI following contrast-enhanced CT scans performed before TAVI.
  • To assess secondary outcomes including renal replacement therapy and 30-day mortality.

Main Methods:

  • A prospective study involving 359 patients undergoing pre-TAVI CT.
  • CI-AKI defined by Kidney Disease-Improving Global Outcomes (KDIGO) guidelines.
  • Nonionic, low-osmolality iodinated contrast material used for all CT studies.

Main Results:

  • Overall CI-AKI incidence was 7% (24 patients), with no significant difference between those with and without baseline CKD (4.8% vs. 8%).
  • Only 1.7% of patients experienced AKI based on three creatinine tests.
  • No patients required new dialysis initiation within 30 days post-CT.

Conclusions:

  • CI-AKI following pre-TAVI CT is low, even in patients with CKD.
  • The majority of CI-AKI cases were transient and did not necessitate dialysis.
  • Routine avoidance of CT in patients with CKD prior to TAVI may not be necessary.

Keywords:
TAVIchronic kidney diseasecomputed tomographycontrast-induced acute kidney injuryiodinated contrastrenal function

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