Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

5.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Smartphone Applications in Dermatology With Special Focus on AI: A European-Continent-Based Review.

International journal of dermatology·2026
Same author

Simulated daylight versus conventional PDT for mild to moderate actinic keratoses: A randomized controlled trial.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Biopsy site identification in surgical dermatology: a review of current techniques and the emerging role of ultraviolet-induced fluorescent dermoscopy.

Italian journal of dermatology and venereology·2026
Same author

Use of dupilumab in the management of refractory prurigo nodularis in an immunosuppressed double transplanted patient.

Anais brasileiros de dermatologia·2026
Same author

Perspectives on Artificial Intelligence in Dermatology: An International Cross-Sectional Study.

Medicina (Kaunas, Lithuania)·2026
Same author

Beyond lacunae: Dermoscopic features of angiomas.

JAAD international·2026

Related Experiment Video

Updated: Jan 7, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

2.8K

Streamlined Management of Basal Cell Carcinoma with Dermoscopy: A Retrospective Case-Control Study.

Francisca Donoso1, Rosario Aguero1, Marie-Chantal Caussade1

  • 1Department of Dermatology, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8330077, Chile.

Journal of Clinical Medicine
|December 30, 2025
PubMed
Summary

Directly excising basal cell carcinoma (BCC) after clinical and dermoscopic diagnosis, without a biopsy, improves accuracy and efficiency. This streamlined approach reduces patient visits and healthcare costs for BCC management.

Keywords:
Mohs micrographic surgerybasal cell carcinomaskin cancersurgerywide local excision

More Related Videos

Establishment of a Clinic-based Biorepository
07:50

Establishment of a Clinic-based Biorepository

Published on: May 29, 2017

6.8K
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

516

Related Experiment Videos

Last Updated: Jan 7, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

2.8K
Establishment of a Clinic-based Biorepository
07:50

Establishment of a Clinic-based Biorepository

Published on: May 29, 2017

6.8K
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

516

Area of Science:

  • Dermatology
  • Oncology
  • Surgical Pathology

Background:

  • Standard basal cell carcinoma (BCC) management requires biopsy before treatment, increasing healthcare costs and patient visits.
  • Evaluating alternative diagnostic and treatment pathways for BCC is crucial for improving efficiency.

Purpose of the Study:

  • To assess the effectiveness of direct surgical excision for clinically and dermoscopically diagnosed BCCs, bypassing the need for a preliminary biopsy.
  • To compare diagnostic accuracy, margin status, and treatment outcomes between a streamlined approach and traditional biopsy-guided treatment.

Main Methods:

  • A retrospective case-control study involving 389 BCCs at a tertiary cancer center.
  • Lesions were divided into a streamlined treatment group (direct excision or curettage/electrosiccation) and a biopsy group.
  • Analysis of clinical and histopathological data to compare diagnostic accuracy and treatment outcomes.

Main Results:

  • The streamlined group showed higher diagnostic accuracy (94.6% confirmed BCC) compared to the biopsy group (73.4%).
  • Direct excision with a 4 mm margin in the streamlined group achieved clear margins in 97.9% of cases.
  • Margin involvement was significantly associated with high-risk and recurrent BCCs.

Conclusions:

  • Direct excision without prior biopsy is an efficient, cost-effective strategy for managing BCC, reducing patient burden.
  • This streamlined approach is particularly beneficial for low-risk BCCs and older patients.
  • Advances in dermoscopy enhance diagnostic accuracy, supporting this feasible option, especially in resource-limited settings.