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Updated: Jan 7, 2026

Electromagnetic Navigation Transthoracic Nodule Localization for Minimally Invasive Thoracic Surgery
Published on: May 4, 2022
Portable Cone-Beam Computed Tomography System for Intraoperative Localization of Pulmonary Nodules: An Initial
Masahiro Mitsuoka1, Nagiko Mitsuoka1, Yuichiro Ueta1
1Department of Surgery, Kurume University School of Medicine, Fukuoka, 830-0011, Japan.
Objectives:
Advances in imaging have expanded options for diagnosis and therapy, including wedge resection of small pulmonary nodules. Cone-beam computed tomography (CBCT) can substitute for hybrid operating rooms (ORs) to identify impalpable nodules. We report the initial clinical use of a portable CBCT system (Cios Spin, Siemens, Germany) for intraoperative localization of small pulmonary nodules.
Methods:
Four patients (3 men, 1 woman; mean age, 68.3 years) with peripheral nodules were included. Under general anaesthesia, an initial pre-scan confirmed that the lesion was within the field of view. Thoracoscopic surgery was initiated, and a surgical clip was placed on the visceral pleura at the site predicted from preoperative computed tomography (CT) to be closest to the tumour. During surgery, the C-arm was removed and later repositioned for intraoperative scanning.
Results:
All nodules, 1.4-cm ground-glass, 2.0-cm part-solid, and two 0.7-cm, were clearly visualized, with image quality comparable to preoperative CT. The portable system accommodated table flexion and lateral decubitus positioning. No complications occurred, and radiation exposure, measured in one case, was acceptable.
Conclusions:
To our knowledge, this is the first report to demonstrate that portable CBCT enables accurate, flexible, and real-time intraoperative localization of pulmonary nodules without requiring a hybrid OR.

