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Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
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A Systematic Comparison of Implementation Strategies at Three U.S. Clinic Settings That Expanded Access to

Jennifer Karlin1, Tammy Bennett, Leah Michael

  • 1Department of Family and Community Medicine, University of California, San Francisco, San Francisco, CA (J.K.); Department of Pediatrics, The Ohio State University College of Medicine and Division of Adolescent Medicine, Nationwide Children's Hospital, Columbus, OH (T.B.); Louisiana Department of Health, Bureau of Family Health, Reproductive Health Program (L.M.); and Louisiana Department of Health, Office of Public Health (S.R.), New Orleans, LA; and Birth Control Pharmacist and Department of Pharmacy, UC San Diego Health, San Diego, CA (E.D.B.).

Obstetrical & Gynecological Survey
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PubMed
Summary

Subcutaneous depot medroxyprogesterone acetate (DMPA) in prefilled syringes simplifies self-administration. This innovation enhances contraceptive accessibility by reducing the need for clinical visits.

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Area of Science:

  • Reproductive Health
  • Pharmacology

Background:

  • Depot medroxyprogesterone acetate (DMPA) is a widely used contraceptive.
  • Current administration often requires clinical settings.

Purpose of the Study:

  • To evaluate the accessibility and ease of use of subcutaneous DMPA.
  • To explore the potential of self-administration to improve contraceptive access.

Main Methods:

  • Review of the formulation and delivery system of subcutaneous DMPA.
  • Analysis of the implications of prefilled, single-dose syringes for administration.

Main Results:

  • The subcutaneous formulation of DMPA is available in prefilled, single-dose syringes.
  • This format facilitates easy self-administration or administration by a non-clinician.

Conclusions:

  • The subcutaneous DMPA syringe format enhances contraceptive accessibility.
  • Reduced need for clinician visits may improve medication availability and uptake.