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The Influence of COVID-19 on the Rate of Symptomatic Deep Venous Thrombosis Following Foot and Ankle Surgery

Nevin Joseph1, Alex Bischoff2, Meghan Roby1

  • 1*OhioHealth Grant Medical Center, Columbus, OH.

Journal of the American Podiatric Medical Association
|December 30, 2025
PubMed

Insights

This study found no increased risk of deep vein thrombosis (DVT) after foot and ankle surgery in patients with coronavirus disease 2019 (COVID-19). No specific risk factors were identified for DVT in this patient group.

Area of Science:

  • Orthopedic Surgery
  • Vascular Surgery
  • Infectious Diseases

Background:

  • Coronavirus disease 2019 (COVID-19) is associated with a prothrombotic state.
  • Limited research exists on COVID-19's impact on deep venous thrombosis (DVT) post-surgery.
  • This study investigates DVT incidence and risk factors in COVID-19-positive patients undergoing foot and ankle surgery.

Purpose of the Study:

  • To evaluate the incidence of deep venous thrombosis (DVT) in patients who underwent foot and ankle surgery and had a positive COVID-19 diagnosis.
  • To identify potential risk factors influencing DVT development in this specific patient cohort.

Main Methods:

  • A retrospective review was conducted at a single institution.
  • Included patients had a COVID-19 positive diagnosis and underwent foot or ankle surgery.
  • A comparison was made between 321 COVID-19 positive patients and 151 patients without COVID-19.

Main Results:

  • The incidence of DVT in COVID-19 positive patients was 3.12%, which was not significantly higher than the 1.99% in the no COVID-19 group (P = .463).
  • No demographic, medical history, vaccination status, or surgical factors demonstrated a statistically significant influence on DVT rates.
  • Key factors like timing of diagnosis, trauma, surgical location, and prophylaxis use were not significant predictors.

Conclusions:

  • The study did not find evidence that COVID-19 increases the risk of DVT following foot and ankle surgery.
  • No specific variables were identified as significant risk factors for DVT in COVID-19 positive patients undergoing these procedures.
  • Larger population studies are recommended for further investigation into DVT rates in COVID-19 patients post-foot and ankle surgery.
Abstract

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