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Fibrous Dysplasia in Craniosynostosis
Lauren Middleton1, Pragaash Shanmuganathan1, Peter Anderson1,2
1Cleft and Craniofacial SA, The Women's and Children's Hospital, Adelaide, SA, Australia.
Purpose:
This case series presents 2 pediatric patients diagnosed with craniosynostosis who subsequently developed fibrous dysplasia. The aim is to describe their clinical presentation, management, and outcomes.
Methods:
A retrospective chart review was conducted at Cleft and Craniofacial SA, Women's and Children's Hospital, Adelaide, South Australia. Medical histories, examinations, imaging, and longitudinal follow-up data were analyzed.
Results:
Two patients with craniosynostosis with fibrous dysplasia were identified. Firstly, a 13-year-old male with sagittal synostosis, underwent cranial vault remodeling at 7 months of age. The second patient, a 16-year-old female with metopic synostosis, managed without surgical intervention, with craniofacial growth closely monitored from childhood into adolescence. Both demonstrated stable cranial morphology on follow-up, without progression or neurological compromise.
Conclusion:
While these 2 associations could be independent events, these 2 cases raise the possibility of a previously unrecognized association between craniosynostosis and fibrous dysplasia.
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